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EPIDEMIOLOGY AND DISEASE BURDEN OF MASLD/MASH MASLD is estimated to impact around 32.4% of adults across the world and is currently considered the leading chronic liver disease globally, with estimates exceeding one billion individuals affected [13,14]

Three residues (V16 P , Y19 P and L20 P ) engage in stacking and hydrophobic contacts with the sidechains of TM2 and ECL1 residues including L201 2.71b , Y205 2.75b and A208 ECL1

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Medication interactions: Berberine may interact with certain medications, specifically anti-rejection drugs taken after an organ transplant